One of lithium’s most fascinating effects is that it promotes neuronal repair in the hippocampus by turning on the growth of new brain cells. Remarkably, this miracle mineral not only prevents and reverses age-related cerebral atrophy but has even proven helpful in the treatment of traumatic brain injury.įighting off neurodegenerative diseases requires that the brain replace damaged neurons. And it enhances brain size, optimizes cognitive health, improves memory, and boosts overall brain function. It strengthens nerve cell connections in brain regions that are involved in regulating mood, thinking, and behavior. In just the past few years numerous research studies have shown that low-dose lithium blocks the molecular dysfunctions that trigger the onset of Alzheimer’s disease and reverses the progression to cognitive decline. These doses are very effective and do not cause side effects or adverse reactions. Typical daily intakes for low-dose lithium are much smaller, ranging from 20 to 80 mg a day. Low-dose (or microdose) lithium is an essential mineral nutrient (like calcium, magnesium, or zinc) that is necessary for human survival and works to harmonize metabolic function in the central nervous system. Typical doses for bipolar disorder and mania range from 500 to 2,000 mg a day. High-dose lithium is a potentially toxic pharmaceutical used as a drug to treat severe mental illness. To understand lithium, you need to appreciate the distinction between high-dose lithium and low-dose lithium. A few months later I read a research article in the Lancet showing that low-dose lithium reversed cerebral atrophy, so I added 20 milligrams (mg) a day of lithium orotate to my supplement program.Ībout five years after the first scan, a repeat MRI revealed that the atrophy was completely gone! Recent research has unveiled the mechanism: lithium triggers the production of BDNF (brain-derived neurotrophic factor), which stimulates the growth of stem cells, leading to neuroregeneration. When an MRI scan of my brain showed cerebral atrophy a number of years ago, it wasn’t surprising most people experience some brain shrinkage as a “normal” feature of aging.
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